A Guide to 2nd Line Treatments and New Treatments on the Horizon

Hear from Dr. Susan Shenoi on how to unlock the knowledge you need to make informed decisions about 2nd line treatments and the promising new therapies on the horizon. In this town hall, you will understand the next steps in your treatment journey, and be empowered with the latest insights and options.


Dr. Shenoi’s town hall details:

A basic understanding of JM – Dr. Shenoi describes myositis as a pizza topping analogy. Myositis is the base and the autoantibodies are the toppings. This analogy paints the picture of the many different disease courses in juvenile dermatomyositis and how unique they are.

Immune System Pathways – Dr. Shenoi provides a graphic of the immune system’s makeup that is really interesting and shows how different drugs target different pathways.

Combination Therapy – Since there is not an exact science as to which immune pathway to target, Dr. Shenoi and other JM experts believe that “combination therapy” is ideal for treatment. For example, abatacept might target the T-cell path, while Rituximab targets the B-cells. The combination of drugs targeting multiple immune system paths creates better outcomes.

Who should know these options – The primary goal of adding 2nd or 3rd line treatment options is to reduce and eliminate prednisone (steroids) as it comes with long term side effects. These options will hopeful allow for more control of the juvenile myositis without steroids and optimize a patients quality of life!

    Shevlin & Smiddy Families Unite to Build Community

    One such alliance in the Seattle area is that of the Shevlin and Smiddy families. These two families have come together to host community events that make Cure JM’s crucial work possible. Their approach has been to keep it simple with a “yard sale” yet, the event has become a staple in their community and a way for JM and families and friends to stay connected year after year.

    Walking Strong, Empowered by unity

    Walking Strong – Empowered by Unity

    Like other teens new to the JM journey, Catie Beth Caldwell and Madi Cook were two individuals who felt alone at the beginning of their journeys. Catie Beth was diagnosed just before the Covid-19 pandemic took hold of the world as we knew it. With this came feelings of isolation and loneliness. These emotions were commonplace for many teens but were only compounded by teens new to a rare disease diagnosis. These first years of the “new normal” were difficult to navigate.

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