Your JM Support Community
Cure JM is powered by a community of families who have successfully navigated the JM journey and are here to help you do the same.
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Cure JM is the global leader in juvenile myositis (JM) research. We are paving the way to better treatments for JM while improving the lives of families affected by the disease.
About
Juvenile Myositis
Juvenile myositis involves a run-away immune response where the body’s immune system attacks its own cells and tissues. With proper treatment and care, children can go on to live their best lives.
We are honored to share our new short film, “Our Mission, Our Impact,” highlighting the key aspects of our mission, working together to make life-changing impacts for the patients and families we serve. Please join us in celebrating the impacts of this progress by making a gift and sharing this video.
Resources
Getting the Diagnosis
It often takes a bit of time for children with juvenile myositis (JM) to get a proper diagnosis. This is due to the fact that
Treatment Plans for Juvenile Myositis
A treatment plan is based on many factors, including the severity and expression of the juvenile dermatomyositis (JDM). Each case is different and the symptoms
DIY Fundraising
Fundraising doesn’t have to be a daunting task…We’d like to invite our families to join us in putting the “Fun” in fundraising.
Get Involved
Discover the many ways you can support and connect with Cure JM.
We invite you to get involved with Cure JM. We hope you’ll join us in helping make our mission a success.
Cure JM families and friends are joining forces to become Hope Heroes. Join the hundreds of Cure JM families who are taking action to help find a cure for JM.
Join us anytime between now and Giving Tuesday, December 3, to help give JM kids a brighter future. Together, we can fund better treatments, care, and support for juvenile myositis.
Finding a Cure and Better Treatments for Juvenile Myositis
Cure JM is accelerating juvenile myositis research at an unprecedented pace. We are pursuing promising new treatments, funding clinical trials, and improving care for patients.
Research
New Treatments
Trials
Care Network
Current Research Updates
With your financial support, Cure JM is proud to have funded Fionnuala McMorrow, a Postgraduate Research Student in the Department of Life Sciences at the University of Bath, to embark on a critical research project. Fionnuala’s team analyzed blood samples from the UK to investigate two specific biomarkers (anti-CCAR1 and anti-Sp4) recently identified in U.S. patients with JDM and related conditions.
Last year, Cure JM and a team of collaborative researchers received a prestigious $2 million grant from the Chan Zuckerberg Initiative to advance our understanding of juvenile myositis (JM). The goal? To discover new markers in the blood that could lead to more precise, personalized care for children with JM. We are excited to share some of the early results from this research.
The generous support of our community has been instrumental in funding groundbreaking research this year, led by Dr. Christian Lood at the University of Washington and Cure JM’s Center of Excellence at Seattle Children’s Hospital. Dr. Lood’s team has identified calcified mitochondria in the muscle tissue of JDM patients with calcinosis – a finding that sheds new light on understanding JDM.
Cabaletta Bio Presents Promising Early Data for CAR-T in Myositis
Exciting news from the European Congress of Rheumatology (EULAR) 2024 last month in Vienna, Austria! Cure JM partner Cabaletta Bio, presented encouraging results from their CAR-T cell therapy, CABA-201, in treating myositis.
The Chan Zuckerberg Initiative has awarded Cure JM and a consortium of Cure JM-funded researchers a coveted $2 million rare disease research grant to identify new biomarkers in JM and improve precise, personalized care through the identification of cell-to-cell interactions that drive inflammation in juvenile myositis.
A clinical trial treating patients with juvenile myositis with the drug abatacept resulted in lower disease activity and clinically significant responses in most patients.
“Cure JM has provided us so much support and connected us to so many families that were experiencing or had experienced the exact same thing. That sense of community helped us get through the ups and downs.”
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